You can buy Rezurock at the lowest price in the online pharmacy Nextgen.ooo . Belumosudil is used in the treatment of chronic graft-versus-host disease and has been investigated for the treatment of pulmonary arterial hypertension. It is an inhibitor of ROCK, with significantly more selectivity for ROCK2 as compared to ROCK1 (IC50 100 nM vs. 3 μM, respectively). In the treatment of graft-versus-host disease, a condition in which donor T-cells begin to attack recipient tissues following allogeneic hematopoeitic stem cell transplantation, belumosudil helps to resolve immune dysregulation by shifting the balance between Th17 cells and T-regulatory cells, thereby dampening the inflammatory cascade that can occasionally be fatal.
 
Belumosudil was first approved by the FDA in July 2021, under the brand name Rezurock, for the treatment of chronic graft-versus-host disease in patients who have tried and failed at least two prior lines of systemic therapy.