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Abirakast (abiraterone)

You can buy Abirakast at the lowest price in the online pharmacy Nextgen.ooo . Abiraterone is an antiandrogen used in the treatment of prostate cancer. Abiraterone is a derivative of the steroid progesterone and is an innovative drug that offers clinical benefits for patients with hormone-resistant prostate cancer. Abiraterone is administered as an acetate salt prodrug because it has higher bioavailability and is less susceptible to hydrolysis than abiraterone itself. FDA approved on April 28, 2011. Abiraterone is associated with a decrease in PSA levels, tumor size reduction, radiographic regression of bone metastases, and pain relief.

 

Abiraterone is an orally active inhibitor of the steroid enzyme CYP17A1 (17-alpha-hydroxylase / C17,20-lyase). It selectively and irreversibly inhibits CYP17A1 through a covalent binding mechanism. CYP17A1 is an enzyme that catalyzes androgen biosynthesis and is highly expressed in testicular, adrenal, and prostate tumor tissue. Specifically, abiraterone inhibits the conversion of 17-hydroxyprognenolone to dehydroepiandrosterone (DHEA) by CYP17A1, reducing serum levels of testosterone and other androgens.

Abirakast (abiraterone)

$170.00Price
Quantity
  • General information

    Active ingredient - Abiraterone

    Original name - Zytiga

    Quantity in package - 120 pcs.

    Dosage - 250 mg

    Storage temperature - up to 30 ° C

    Country of manufacture - India

    Manufacturer - Aprazer ltd

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