You can buy Lucipirfe at the lowest price in the online pharmacy Nextgen.ooo . Pirfenidone an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis, which is a chronic, progressive form of interstitial pneumonia. While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor pathways and modulate cellular oxidation. The FDA first approved pirfenidone alongside nintedanib as one of the first drugs to treat idiopathic pulmonary fibrosis.
The exact mechanism of action of pirfenidone is not fully understood. It is suggested that the antioxidant effects of pirfenidone contribute to its anti-inflammatory effects, leading to antifibrotic effects. Pirfenidone attenuates the production of transforming growth factor-β1 (TGF-β1), a key profibrotic and pro-inflammatory cytokine implicated in idiopathic pulmonary fibrosis. By suppressing TGF-β1, pirfenidone inhibits TGF-β1-induced differentiation of human lung fibroblasts into myofibroblasts, thereby preventing excess collagen synthesis and extracellular matrix production.
Lucipirfe (pirfenidone)
General information
Active ingredient - Pirfenidone
Original name - Esbriet
Quantity in package - 120 pcs
Dosage - 200 mg
Storage temperature - up to 30 ° C
Country of manufacture - Laos
Manufacturer - Lucius Pharmaceuticals